My business, currently located in the North Valley, is looking to move down to Nob Hill. Ideally, we would need about 600 square feet and a storefront.
If you know of anyone looking to transfer a lease or a space opening up, we'd love to talk to you.
I would highly recommend you get to know the neighborhood association folks:
If you're new to the area they could be a tremendous asset to you, not only in maybe knowing the buzz and being able to help you find a location, but by being involved in the association you'll be sure to know about City plans for the neighborhood (ie. Lead/Coal construction).
I am a member of the Nob Hill Main Street group that deals with economic development in Nob Hill. I made a request to send you a personal message, if you accept I can send you more information about Nob Hill rental spaces.
I run a one-woman web development shop and art studio. Currently I rent a space across from the Fruit Basket next to Sophia's where Obama was on 4th street.